Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Increased cyclic AMP concentrations are also associated with the inhibition of release of mediators from mast cells in the airway. Holding the canister upright as shown in Figure 3, between your thumb and finger put the mouthpiece in your mouth and close your lips. Combivent side effects Stop using Combivent and get emergency medical help if you have any of these signs of an allergic reaction: difficulty swelling of your face, lips, tongue, or throat. Use this medication regularly to receive the most benefit from it. Ipratropium bromide: combivent fran indien Although lipid-insoluble quaternary bases pass into breast milk, it is unlikely that the active component, ipratropium bromide, would reach the infant to an important extent, especially when taken by aerosol.